Initiated by the discovery of the JAK2 mutation, the past decade has seen a great deal of activity in the development of potential new therapies for MPNs. Several JAK inhibitor drugs are in clinical trials as well as other therapy types such as stem cell transplant.
Should I participate in a clinical trial?
The decision to take part in a clinical trial is a personal one and should be made with the input of your physician. Clinical trials can provide access to new medications that may be of benefit for treatment of your disease, and the data from clinical trials is of great benefit in helping future patients affected with similar condition. But you also need to consider that these medications are usually experimental and some of the adverse effects may not be known. Participating in a clinical trial may mean a time commitment, with more frequent visits to the trial centre.
Trials for Myelofibrosis
Trials for Polycythemia Vera & Essential Thrombocythemia
Trials for Mastocytosis