Dapoxetine (Priligy)

Dapoxetine is the first official oral drug approved for use in premature ejaculation or premature ejaculation. It is a pill you only take when you need it, about 1-3 hours before sex to start. PE is a very personal matter, but it occurs very often in men. By research sociologist Edward Laumann from 1999 based on National Health and Social Life Survey In 1992, a little less than 30% of all men suffer from this problem, making it the most common sexual dysfunction among men.

What is Created For?

The active ingredient in Priligy called dapoxetine ensures that a serotonin excess is produced in the body. Dapoxetine does this by selectively blocking the reuptake of serotonin in nerve cells and is a so-called SSRI (Selective Serotonin Reuptake Inhibitor). Popular SSRI antidepressants work in a similar way, only that you swallow every day to achieve a similar effect, and may have unpleasant side effects that dapoxetine does not have.

By increasing serotonin levels you get more control over your Priligy ejaculation and the time of ejaculation. The feeling that you control your ejaculation takes frustrations, uncertainties and doubts that normally gets lost from a history of premature ejaculation. Besides the increasing sense of control Priligy has the side effect that you can enjoy sex more and keep a satisfied feeling.

Unknown Effects of Dapoxetine

Men take pride Priligy can experience the following benefits:

  • Increased the time to ejaculation
  • Greater sense of control over ejaculation
  • More mental and physical satisfaction during sex
  • Reduced uncertainties and concerns about premature ejaculation
  • In general, the situation has improved

Pros and Cons

In comparison to Canada and the EU, the rather strict US Food and Drug Administration (FDA) did not certify the active substance as a precursor for the treatment of premature ejaculations at the first attempt in 2005, because many questions remained open. Currently it is in test phase 3 (clinical studies) in the USA, the outcome of this approval process is open. Since 2009 dapoxetine, which has been approved under the trade name Priligy for the treatment of premature ejaculation in Canada, Europe, Mexico, some Asian countries, is on the market. The drug is a prescription, but can be legally ordered online with an online recipe. Since then, there has been a lively discussion about the meaning of this drug, which comes from the group of serotonin reuptake inhibitors, or SSRIs for short. According to the publication in the drug bulletin, however, the successes, depending on how you read the studies on dapoxetine or SSRI, are restrained but present. About one to two minutes, the profit seems to be on average, depending on the dosage sometimes a little more or less.

There is no effect from any drugs without potential side effects, but both should be balanced against each other. A benefit of dapoxetine in premature ejaculation certainly is meaningful, even if the time gain is not immense. The available dosages are 30mg and 60mg at 3, 6, 9 or 12 tablets per pack, larger packages, such as in case of PDE5 inhibitors, do not yet exist.

Priligy should not be taken daily due to this mode of action. Because a permanently increased serotonin level reduces the number of receptors to which the messenger substance docks. The body notices that there is always too much serotonin and therefore replaces the sites where it is effective. Taking Priligy Dapoxetine on a daily basis, on the one hand, would mean that the dose must be steadily increased because the receptors are steadily decaying, and secondly, one would be in a bad mood after the drug is subsequently discontinued until new receptors are formed. The effect of the regression of the receptors is reversible, as we said before – the body can also provide new receptors if it has degraded over a period of time.

The remedy works like all other SSRIs, which are mostly used as antidepressants, directly in the Gehrin and prevents there the removal of the messenger substance serotonin. In contrast to other similar drugs, the remedy works relatively quickly, within a good 2-3 hours. The intake should therefore take place in good time before sexual intercourse, taken too soon before dapoxetine remains ineffective. The rapid effect is also associated with a rather short action window / a short half-life, we recommend sexual intercourse within 3 hours after ingestion. The standard dosage is 30 mg as a single daily dose, in consultation with the attending physician, it can be increased in individual cases up to 60 mg per day.

Since the brain and spinal cord play a central role in the time of ejaculation, the ejaculating reflex is delayed by the damping and relaxing effect. Incidentally, other disturbing factors such as excitement or anxiety are lowered.

You do not need to swallow them every day like it was previously necessary with anti-depressants. Priligy works fast and is also broken down relatively quickly by your body, so you will not suffer from the excessive side effects that most anti-depressants are notorious for, such as a decrease in libido. Also, the use of Priligy has a positive effect on the (sexual) relationship between you and your partner due to the increased time to ejaculation.

Priligy is only available with a prescription from your doctor. This medicine is not reimbursed by your health insurance, so you have to pay for yourself – along with the cost of medical advice.

Possible Side Effects

The benefits described above are offset by the potential side effects of this drug and other such psychopharmaceuticals. Starting with rather harmless, but well-being sensitive side effects such as nausea, diarrhea, vomiting, headache, dry mouth, sweating, weight changes and listlessness to erectile dysfunction, changes in blood pressure and loss of consciousness. Also, the amount of possible interactions and contraindications speaks for a conscientious clarification by a doctor. In particular, when taking on a sufficient hydration, to pay attention to those who drink too little increases risk of serious circulatory problems. Also, alcohol should not be consumed when taking Priligy. The use of machinery or road traffic should be avoided, especially because of the low but present risk of syncope (circulatory collapse). Do not take Priligy if you have heart or liver disease, depression or take certain psychotropic drugs.


The information provided on the website is created using the best practices and efforts to provide comprehensive and accurate descriptions, but errors and omissions may occur. This information should not be used for self-diagnosing or drawing any conclusions about users’ health; nor should it be used to disregard or deviate from the recommendations given by medical professionals; licensed healthcare practitioners should be consulted to this end.

The materials and comments given on this website should never be regarded as a basis for interpretation, acting on or using as grounds for self-administration of any drugs. Users are reminded of the importance of seeking timely professional help for matters concerning diagnosing, healthcare advising and drug prescription.

References to commercial products available at Mpncanada.com should not be viewed as a recommendation for application in any specific condition, endorsement or promotion of any kind by our website or that of our partners and related parties.